# EndoGuide — NiTi File Root Canal Treatment Protocol Reference

> EndoGuide is a free clinical reference for endodontic NiTi rotary and reciprocating file systems: manufacturer-sourced file specifications (tip size, taper, speed, torque), step-by-step shaping protocols, clinical tips and warnings, evidence-linked references, plus clinical guides and decision tools for root canal treatment. Content is written and reviewed by an endodontist and hedged by design — it supports, never replaces, clinical judgment and the official instructions for use.

- **Author:** Uzm. Dt. Levent Yüksel — [About the author](https://endo-guide.app/about.md)
- **File systems:** 66

## Start here

- [Find Your File](https://endo-guide.app/find-your-file.md): case-matching wizard — ranks systems by canal curvature, canal shape, motion preference and clinician experience (score-only, no brand weighting)
- [Compare Systems](https://endo-guide.app/compare.md): side-by-side specs for any two systems plus curated comparison pages
- [Assess Case Difficulty](https://endo-guide.app/difficulty.md): 17-question case-difficulty scoring with critical flags
- [Motor Settings](https://endo-guide.app/motor-settings.md): speed and torque reference across systems
- [File Sizes](https://endo-guide.app/file-sizes.md): ISO tip sizes, tapers and colour codes explained
- [Glossary](https://endo-guide.app/glossary.md): endodontic terminology with definitions
- [NiTi File Collections](https://endo-guide.app/niti-files.md): curated collections by motion, alloy and use case
- [Pedodontic File Systems](https://endo-guide.app/pedodontics.md): primary-tooth systems with source-audited intended-use labels

## File systems by manufacturer

### Dentsply Sirona Systems

The ProTaper family and WaveOne Gold combine multi-step rotary and single-file reciprocating approaches. ProGlider provides single-file mechanical glide path preparation. TruNatomy focuses on dentin-preserving geometry, Vortex Blue offers blue heat-treated crown-down versatility.

- [ProTaper Gold®](https://endo-guide.app/system/protaper-gold.md): Gold Heat-Treated Progressive Taper — Gold Heat-Treated NiTi · Continuous Rotation · 8 files
- [ProTaper Ultimate™](https://endo-guide.app/system/protaper-ultimate.md): M-Wire, Gold & Blue Slider-Shaper-Finisher — M-Wire / Gold / Blue Heat-Treated NiTi · Continuous Rotation · 8 files
- [ProTaper Next®](https://endo-guide.app/system/protaper-next.md): Progressive Efficiency — M-Wire NiTi · Continuous Rotation · 6 files
- [WaveOne Gold®](https://endo-guide.app/system/waveone-gold.md): Single File Reciprocation — NiTi with proprietary Gold heat treatment · Reciprocating · 5 files
- [ProGlider®](https://endo-guide.app/system/proglider.md): Mechanical Glide Path in One File — M-Wire NiTi · Continuous Rotation · 1 file
- [PathFile®](https://endo-guide.app/system/pathfile.md): Three-File Mechanical Glide Path Sequence — Conventional NiTi · Continuous Rotation · 3 files
- [TruNatomy®](https://endo-guide.app/system/trunatomy.md): True, Natural, Anatomy — Heat-Treated NiTi · Continuous Rotation · 6 files
- [Vortex Blue®](https://endo-guide.app/system/vortex-blue.md): Blue Wire Crown-Down — Blue Heat-Treated NiTi · Continuous Rotation · 16 files

### VDW Systems

Mtwo is the globally established Simultaneous Shaping system with a 4-file basic sequence. RECIPROC is the original single-file reciprocating workflow, Reciproc Blue adds a blue heat-treated variant, and VDW.ROTATE offers a simplified 3-file rotary sequence.

- [Mtwo®](https://endo-guide.app/system/mtwo.md): The Efficient NiTi System — Conventional NiTi · Continuous Rotation · 16 files
- [RECIPROC®](https://endo-guide.app/system/reciproc.md): Original Single-File Reciprocation — M-Wire NiTi · Reciprocating · 3 files
- [Reciproc® blue](https://endo-guide.app/system/reciproc-blue.md): Blue Heat-Treated, Pre-Bendable Reciprocation — M-Wire NiTi with Blue heat treatment · Reciprocating · 3 files
- [VDW.ROTATE®](https://endo-guide.app/system/vdw-rotate.md): Simplified Rotary Efficiency — Heat-Treated NiTi · Continuous Rotation · 13 files

### Coltene Systems

HyFlex EDM uses controlled memory behavior and EDM manufacturing technology for superior fatigue resistance. HyFlex CM offers the original pre-bendable controlled-memory wire with a versatile multi-file hybrid technique.

- [HyFlex® EDM](https://endo-guide.app/system/hyflex-edm.md): Controlled Memory — CM-Wire (EDM manufactured) · Continuous Rotation · 8 files
- [HyFlex® CM](https://endo-guide.app/system/hyflex-cm.md): Controlled Memory — CM-Wire (Controlled Memory NiTi) · Continuous Rotation · 6 files
- [HyFlex® GPF](https://endo-guide.app/system/hyflex-gpf.md): Controlled Memory Glide Path Files — CM-Wire (Controlled Memory NiTi) · Continuous Rotation · 3 files

### FKG Dentaire Systems

iRaCe offers a simplified 3-file sequence; BioRaCe provides the Debellian & Trope biological approach with a 10-file range. XP-endo Shaper targets 3D contact through adaptive expansion; XP-endo Finisher completes with 3D cleaning. R-Motion offers reciprocating shaping with blue heat-treated NiTi.

- [iRaCe®](https://endo-guide.app/system/irace.md): 3-File Simplicity — Conventional NiTi (Electropolished) · Continuous Rotation · 5 files
- [BioRaCe®](https://endo-guide.app/system/biorace.md): Biological Root Canal Preparation — Conventional NiTi (Electropolished) · Continuous Rotation · 10 files
- [XP-endo® Shaper](https://endo-guide.app/system/xp-endo-shaper.md): Adaptive Core — MaxWire (NiTi alloy) · Continuous Rotation · 2 files
- [XP-endo® Finisher](https://endo-guide.app/system/xp-endo-finisher.md): 3D Canal Cleaning — MaxWire NiTi · Continuous Rotation · 3 files
- [XP-endo® Retreatment](https://endo-guide.app/system/xp-endo-retreatment.md): Adaptive Retreatment Sequence — MaxWire (NiTi alloy) · Continuous Rotation · 3 files
- [XP-endo® Rise](https://endo-guide.app/system/xp-endo-rise.md): 2-in-1 Agile Spirit — MaxWire (NiTi alloy) · Continuous Rotation · 2 files
- [iRaCe® Plus](https://endo-guide.app/system/irace-plus.md): Extended Difficult-Canal Sequence — Conventional NiTi (Electropolished) · Continuous Rotation · 4 files
- [RACE EVO™](https://endo-guide.app/system/race-evo.md): Heat-Treated 1-2-3 Sequence — Heat-Treated NiTi (Blue) · Continuous Rotation · 3 files
- [R-Motion®](https://endo-guide.app/system/r-motion.md): Swiss Precision Reciprocation — Heat-Treated NiTi · Reciprocating · 7 files

### Micro-Mega (COLTENE) Systems

One Shape is the original single-file continuous rotation system with variable asymmetric cross-section. 2Shape provides a two-file workflow with T.Wire heat treatment. One Curve offers single-file rotary shaping with C.Wire controlled memory alloy.

- [One Shape®](https://endo-guide.app/system/one-shape.md): Single-File Rotary Simplicity — Conventional NiTi · Continuous Rotation · 1 file
- [2Shape®](https://endo-guide.app/system/two-shape.md): Two-File Simplicity — T.Wire Heat-Treated NiTi · Continuous Rotation · 4 files
- [One Curve®](https://endo-guide.app/system/one-curve.md): Single-File Simplicity — C.Wire NiTi · Continuous Rotation · 4 files
- [One RECI®](https://endo-guide.app/system/one-reci.md): Single-File Reciprocating Shaping — C.Wire (heat-treated NiTi) · Reciprocating · 5 files
- [One Flare®](https://endo-guide.app/system/one-flare.md): Coronal Pre-Flaring Instrument — T.Wire (heat-treated NiTi) · Continuous Rotation · 1 file

### Kerr Dental Systems

TF Adaptive features adaptive motion technology with automatic rotary-reciprocal switching based on stress. ZenFlex focuses on flexibility with controlled memory and minimal invasive purple oxide surface.

- [TF Adaptive™](https://endo-guide.app/system/tf-adaptive.md): Rotary When You Want It, Reciprocation When You Need It — R-Phase NiTi (Twisted) · Adaptive · 6 files
- [ZenFlex™](https://endo-guide.app/system/zenflex.md): Controlled Memory Precision — Heat-Treated NiTi (Controlled Memory) · Continuous Rotation · 10 files
- [K3XF™](https://endo-guide.app/system/k3xf.md): R-Phase Enhanced K3 Design — R-Phase™ Heat-Treated NiTi · Continuous Rotation · 24 files
- [Traverse™](https://endo-guide.app/system/traverse.md): Own the Glide Path — NiTi · Continuous Rotation · 3 files

### EdgeEndo Systems

EdgeFile X7 is a Fire-Wire heat-treated multi-file rotary system with dual taper (.04/.06) crown-down technique and 5x fatigue resistance. EdgeOne Fire is a FireWire reciprocating single-file system compatible with WaveOne Gold motor settings.

- [EdgeFile® X7](https://endo-guide.app/system/edgefile-x7.md): Fire-Wire Crown-Down Rotary — Fire-Wire™ Annealed Heat-Treated NiTi · Continuous Rotation · 14 files
- [EdgeOne Fire™](https://endo-guide.app/system/edgeone-fire.md): FireWire Reciprocation — FireWire™ Heat-Treated NiTi · Reciprocating · 5 files
- [EdgeTaper Platinum™](https://endo-guide.app/system/edgetaper-platinum.md): ProTaper-Compatible FireWire Sequence — FireWire™ Heat-Treated NiTi · Continuous Rotation · 8 files
- [EdgeGlidePath™](https://endo-guide.app/system/edgeglidepath.md): FireWire Rotary Glide Path — FireWire™ Heat-Treated NiTi · Continuous Rotation · 1 file
- [EdgeEvolve™](https://endo-guide.app/system/edgeevolve.md): Moderate Access, Deep Apical Shape — FireWire™ Heat-Treated NiTi · Continuous Rotation · 21 files

### Brasseler USA Systems

EndoSequence features the patented Alternating Contact Point (ACP) design with crown-down technique. ESX offers a streamlined two-file ACP workflow with electropolished finish and patented Booster Tip.

- [EndoSequence®](https://endo-guide.app/system/endosequence.md): Crown-Down Precision — Conventional NiTi (Electropolished) · Continuous Rotation · 9 files
- [ESX™](https://endo-guide.app/system/esx.md): Two-File Shaping with Patented Booster Tip — Electropolished NiTi · Continuous Rotation · 8 files

### Easy Equipamentos (MK Life) Systems

ProDesign Logic uses Controlled Memory (CM) NiTi wire with pre-bendable flexibility, integrated glide path files, and dual shaping series (.03 conservative, .05 standard) — developed and manufactured in Brazil.

- [ProDesign Logic®](https://endo-guide.app/system/prodesign-logic.md): Controlled Memory Flexibility — Controlled Memory NiTi (CM Wire) · Continuous Rotation · 10 files

### Eighteeth Systems

E-Flex Gold offers a cost-effective gold heat-treated Control Memory NiTi system with integrated orifice opener, glider, and shaping files — all at a uniform 350 RPM / 2 Ncm setting.

- [E-Flex Gold](https://endo-guide.app/system/e-flex-gold.md): Gold Heat-Treated Economy — Control Memory NiTi (gold heat-treated) · Continuous Rotation · 9 files

### Inci Dental (Turkey) Systems

The EndoArt family covers both rotary and reciprocating needs with Gold and Blue heat treatment options.

- [EndoArt® Action](https://endo-guide.app/system/endoart-action.md): Turkish Heat-Treated Innovation — Gold/Blue Heat-Treated NiTi · Continuous Rotation · 12 files
- [EndoArt® Touch](https://endo-guide.app/system/endoart-touch.md): Fixed 06 Taper Precision — Gold/Blue Heat-Treated NiTi · Continuous Rotation · 19 files
- [EndoArt® Smart](https://endo-guide.app/system/endoart-smart.md): Fixed 04 Taper Flexibility — Gold/Blue Heat-Treated NiTi · Continuous Rotation · 19 files
- [EndoArt® Expert](https://endo-guide.app/system/endoart-expert.md): Single-File Reciprocating — Gold/Blue Heat-Treated NiTi · Reciprocating · 10 files

### Perfect Dental Systems

Shenzhen Perfect Medical Instruments offers a wide Perfect Dental catalog spanning conventional NiTi (MG3, TS4, TG6, TF4) and heat-treated tiers (MG3 Blue, S-Blue, T-Flex, T-Pro, V-Blue) plus a reciprocating RC family (RC, RC Gold, RC Blue), the PX Wave single-file reciprocating glider, and the K One 15 mm pediatric file. The portfolio covers rotary, reciprocating, hybrid, and pediatric workflows.

- [T-Pro™](https://endo-guide.app/system/perfect-t-pro.md): Mixed Heat-Treatment Sequence — Mixed Heat-Treated + Pre-Bendable NiTi · Continuous Rotation · 6 files
- [V-Blue™](https://endo-guide.app/system/perfect-v-blue.md): Blue NiTi with Convex Triangle Cross-Section — Blue Heat-Treated NiTi · Continuous Rotation · 12 files
- [S-Blue™](https://endo-guide.app/system/perfect-s-blue.md): Entry-Level Heat-Activated System — Blue Heat-Activated NiTi · Continuous Rotation · 4 files
- [T-Flex™](https://endo-guide.app/system/perfect-t-flex.md): High-Purity NiTi Tuned for Curved Canals — High-Purity Black NiTi (low C/O) · Continuous Rotation · 5 files
- [MG3 Blue™](https://endo-guide.app/system/perfect-mg3-blue.md): Heat-Treated MG3 for Improved Flexibility — Blue Heat-Treated NiTi · Continuous Rotation · 5 files
- [MG3™](https://endo-guide.app/system/perfect-mg3.md): Six-File Conventional NiTi Sequence — Conventional NiTi · Continuous Rotation · 6 files
- [TS4™](https://endo-guide.app/system/perfect-ts4.md): Stepped Rotary + Twin Shaper Sequence — NiTi · Continuous Rotation · 5 files
- [TG6™](https://endo-guide.app/system/perfect-tg6.md): Extended Glide-Path + Shaper Sequence — NiTi · Continuous Rotation · 8 files
- [TF4™](https://endo-guide.app/system/perfect-tf4.md): Rotary + Reciprocating Hybrid Sequence — NiTi · Continuous Rotation · 4 files
- [RC Blue™](https://endo-guide.app/system/perfect-rc-blue.md): Blue-Treated Reciprocating Sequence — Blue Heat-Treated NiTi · Reciprocating · 3 files
- [RC Gold™](https://endo-guide.app/system/perfect-rc-gold.md): Gold-Treated Reciprocating Sequence — Gold Heat-Treated NiTi · Reciprocating · 3 files
- [RC™](https://endo-guide.app/system/perfect-rc.md): Reciprocating NiTi — Original — NiTi (conventional) · Reciprocating · 3 files
- [PX Wave™](https://endo-guide.app/system/perfect-px-wave.md): Single-File Reciprocating Glider — NiTi · Reciprocating · 1 file
- [K One™](https://endo-guide.app/system/perfect-k-one.md): Pediatric Single-File for Primary Teeth — NiTi · Continuous Rotation · 1 file

### NIC Dental Systems

NIC Dental (Shenzhen Superline Technology) has manufactured endodontic instruments for over two decades and exports to 70+ countries. Its wire tiers (untreated MaxTech 1.0 plus the MaxTech 3.0 gold, 6.0 blue, 9.0 gray and High Flex CM heat treatments) span the catalog: the U-Series classic-rotation SX–F5 sequence in three wire tiers, the W+ reciprocating single-file system with its Tunnel glide path file, the three-size V Blue reciprocating line with its untreated V File sibling, the KD Blue 500 RPM constant-taper matrix, and the MH High Flex constant-taper range — all documented by the manufacturer's consolidated 2026 fact sheet, draft IFUs, and 2025 catalog.

- [NIC® U-Series](https://endo-guide.app/system/nic-u-series.md): The Familiar Classic — MaxTech NiTi (Untreated / Gold / Blue Tiers) · Continuous Rotation · 24 files
- [NIC® W+](https://endo-guide.app/system/nic-w-plus.md): Gold-Wire Reciprocation — MaxTech 3.0 Gold Heat-Treated NiTi · Reciprocating · 5 files
- [NIC® V Blue](https://endo-guide.app/system/nic-v-blue.md): Three-Size Blue Reciprocation — MaxTech 6.0 Blue Heat-Treated NiTi · Reciprocating · 3 files
- [NIC® V File](https://endo-guide.app/system/nic-v-file.md): Untreated Three-Size Reciprocation — MaxTech 1.0 conventional NiTi · Reciprocating · 3 files
- [NIC® KD Blue](https://endo-guide.app/system/nic-kd-blue.md): Constant-Taper Blue Matrix — MaxTech 6.0 Blue Heat-Treated NiTi · Continuous Rotation · 16 files
- [NIC® MH](https://endo-guide.app/system/nic-mh.md): CM-Wire Constant Taper — MaxTech High Flex CM-Wire NiTi · Continuous Rotation · 14 files

## Clinical guides and reference

### Clinical Guides

- [Emergencies & Antibiotics](https://endo-guide.app/emergencies.md)
- [Complications](https://endo-guide.app/complications.md)
- [Separated Instrument](https://endo-guide.app/separated-instrument.md)
- [Root Perforation](https://endo-guide.app/root-perforation.md)
- [Sodium Hypochlorite Accident](https://endo-guide.app/sodium-hypochlorite-accident.md)
- [Endodontic Flare-Up](https://endo-guide.app/endodontic-flare-up.md)
- [Ledge, Transportation & Patency](https://endo-guide.app/canal-ledge-and-transportation.md)
- [Sealer Extrusion](https://endo-guide.app/sealer-extrusion.md)
- [Pain After Root Canal](https://endo-guide.app/post-root-canal-pain.md)
- [Cracked Tooth & VRF](https://endo-guide.app/cracked-tooth-vertical-root-fracture.md)
- [Diagnosis & Pulp Classification](https://endo-guide.app/diagnosis.md)
- [Diagnosis chart](https://endo-guide.app/endodontic-diagnosis-chart.md)
- [Vertucci Classification](https://endo-guide.app/vertucci-classification.md)
- [Non-Odontogenic Toothache](https://endo-guide.app/non-odontogenic-toothache.md)
- [Perio-Endo Lesions](https://endo-guide.app/perio-endo-lesions.md)
- [Imaging & CBCT](https://endo-guide.app/endodontic-imaging.md)
- [Local Anesthesia](https://endo-guide.app/local-anesthesia.md)
- [Assess Case Difficulty](https://endo-guide.app/difficulty.md)
- [Treatment Steps](https://endo-guide.app/treatment-steps.md)
- [Rubber Dam & Isolation](https://endo-guide.app/rubber-dam-isolation.md)
- [Access Cavity Guide](https://endo-guide.app/access-cavity-guide.md)
- [Access Cavities](https://endo-guide.app/access-cavities.md)
- [Canal Preparation](https://endo-guide.app/canal-preparation.md)
- [Working Length](https://endo-guide.app/working-length.md)
- [Irrigation Protocols](https://endo-guide.app/irrigation.md)
- [Intracanal Medicaments](https://endo-guide.app/medicaments.md)
- [Obturation](https://endo-guide.app/obturation.md)
- [Restoration After Root Canal](https://endo-guide.app/restoration-after-root-canal.md)
- [Single-Visit vs Multiple-Visit](https://endo-guide.app/single-visit-vs-multiple-visit-root-canal.md)
- [Vital Pulp Therapy](https://endo-guide.app/vital-pulp-therapy.md)
- [Regenerative Endodontics](https://endo-guide.app/regenerative-endodontics.md)
- [Apexification & Apexogenesis](https://endo-guide.app/apexification-apexogenesis.md)
- [Dental Trauma](https://endo-guide.app/dental-trauma.md)
- [Tooth Resorption](https://endo-guide.app/tooth-resorption.md)
- [Failed Root Canal](https://endo-guide.app/failed-root-canal-retreatment.md)
- [Endodontic Surgery](https://endo-guide.app/endodontic-surgery.md)
- [Root Canal During Pregnancy](https://endo-guide.app/root-canal-during-pregnancy.md)
- [Root Canal vs Implant](https://endo-guide.app/root-canal-vs-implant.md)
- [How Long Root Canals Last](https://endo-guide.app/how-long-do-root-canals-last.md)
- [Can Antibiotics Cure Infection?](https://endo-guide.app/can-antibiotics-cure-tooth-infection.md)

### Reference

- [By manufacturer](https://endo-guide.app/manufacturer.md)
- [By category](https://endo-guide.app/category.md)
- [By alloy](https://endo-guide.app/alloy.md)
- [Compare Systems](https://endo-guide.app/compare.md)
- [NiTi file collections](https://endo-guide.app/niti-files.md)
- [Single-file systems](https://endo-guide.app/single-file-systems.md)
- [Reusable vs single-use](https://endo-guide.app/reusable-files.md)
- [Pedodontics](https://endo-guide.app/pedodontics.md)
- [Open NiTi Dataset](https://endo-guide.app/niti-dataset.md)
- [IFU change log](https://endo-guide.app/niti-ifu-changes.md)
- [Resources & DFUs](https://endo-guide.app/resources.md)
- [My Kit](https://endo-guide.app/my-kit.md)
- [Find Your File](https://endo-guide.app/find-your-file.md)
- [Assess Case Difficulty](https://endo-guide.app/difficulty.md)
- [Diagnosis Concepts](https://endo-guide.app/concepts.md)
- [Glossary](https://endo-guide.app/glossary.md)
- [Motor Settings](https://endo-guide.app/motor-settings.md)
- [File Sizes (ISO)](https://endo-guide.app/file-sizes.md)
- [Gates-Glidden & Peeso Drills](https://endo-guide.app/gates-glidden-and-peeso-drills.md)
- [Diamond Burs](https://endo-guide.app/diamond-burs.md)
- [Reciprocating vs Rotary](https://endo-guide.app/reciprocating-vs-rotary.md)
- [Heat-Treatment Comparison](https://endo-guide.app/alloy/heat-treatment-comparison.md)
- [About EndoGuide](https://endo-guide.app/about.md)
- [Editorial policy](https://endo-guide.app/editorial-policy.md)
- [Intended use](https://endo-guide.app/intended-use.md)

## Access for agents

- Every page is available as Markdown: request it with `Accept: text/markdown` at the page URL, or append `.md` to the path (`/system/protaper-gold.md`; locale homes use `/index.md`, `/tr/index.md`, `/es/index.md`).
- Responses carry `Content-Type: text/markdown; charset=utf-8`, `Vary: Accept` and a `Link: rel="canonical"` header pointing back to the HTML page.
- Site-level guidance lives in [llms.txt](https://endo-guide.app/llms.txt); the full route inventory is in [llms-full.txt](https://endo-guide.app/llms-full.txt) and [sitemap.xml](https://endo-guide.app/sitemap.xml).
- [Türkçe](https://endo-guide.app/tr/index.md) · [Español](https://endo-guide.app/es/index.md)

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_Educational reference for dental professionals and students. Always confirm settings against the official manufacturer instructions for use before clinical procedures._