Skip to content

Overview

This table records what each manufacturer states about its own sealer, taken from the instructions for use, safety data sheets, technical profiles, brochures and product pages held on file. Nothing here is taken from a journal, a distributor listing or a search result.

A blank cell means the value is not stated in the documents obtained — it does not mean zero, and it has not been filled in from another source. Values are tagged with the document they came from, because only the instructions for use are regulatory labelling; a brochure figure is a manufacturer's marketing claim.

Manufacturer specification table

01AH Plus / AH Plus JetDentsply Sirona

Manufacturer

Dentsply Sirona

Single cone

Master cone only

02AH 26 (silver-free)Dentsply Sirona

Manufacturer

Dentsply Sirona

Single cone

not stated

03AH Plus Bioceramic SealerDentsply Sirona

Manufacturer

Dentsply Sirona

Single cone

Named in the IFU

04BioRoot RCSSeptodont

Manufacturer

Septodont

Single cone

Named in the IFU

05BioRoot FlowSeptodont

Manufacturer

Septodont

Single cone

Named in the IFU

06EndoSequence BC Sealer / BC Sealer HiFlowBrasseler USA

Manufacturer

Brasseler USA

Single cone

Named in the IFU

07TotalFill BC Sealer / BC Sealer HiFlowFKG Dentaire

Manufacturer

FKG Dentaire

Single cone

Named in the IFU

08CeraSealMeta Biomed

Manufacturer

Meta Biomed

Single cone

Named in the IFU

09Bio-C SealerAngelus

Manufacturer

Angelus

Single cone

Named in the IFU

10Bio-C Sealer ION+Angelus

Manufacturer

Angelus

Single cone

Named in the IFU

11BC Universal SealerFKG Dentaire

Manufacturer

FKG Dentaire

Single cone

Master cone only

12MTA FillapexAngelus

Manufacturer

Angelus

Single cone

Named in the IFU

13GuttaFlow biosealColtene / Roeko

Manufacturer

Coltene / Roeko

Single cone

IFU calls for gutta-percha

14GuttaFlow 2Coltene / Roeko

Manufacturer

Coltene / Roeko

Single cone

IFU calls for gutta-percha

15SealapexKerr

Manufacturer

Kerr

Single cone

not stated

16Pulp Canal Sealer EWTKerr

Manufacturer

Kerr

Single cone

not stated

Calcium silicate

AH Plus Bioceramic Sealer

Dentsply Sirona

Composition: Zirconium dioxide 50–70 %, tricalcium silicate 5–15 %, dimethyl sulfoxide 10–30 %, lithium carbonate < 0.5 %, thickening agents < 6 %.

Contraindications

  • The IFU states: none
  • Allergy to any component (listed under warnings)

Handling notes

  • The IFU asks for use immediately after the 24-gauge tip is placed, and states the material can harden in contact with air.
  • Safety and effectiveness are not established in pregnancy, breastfeeding, children or adolescents.
  • In apical external resorption the IFU asks for care to prevent extrusion beyond the canal.

Specification notes

  • Radiopacity: Stated as equivalent to 3 mm of aluminium or more in thickness.
Single cone: The IFU describes use with a gutta-percha master cone and also a sealer-only filling technique.

IFU on file: AH Plus Bioceramic Sealer IFU, NAM EN TDS-V01 2023-06 and EUR multilingual V03 2023-10

BioRoot RCS

Septodont

Composition: Powder based on tricalcium silicate, zirconium oxide and excipients. Aqueous solution of calcium chloride and excipients.

Contraindications

  • Allergy to one of the components

Handling notes

  • The insert asks for a properly placed rubber dam isolating the operating field.
  • With a wide apical foramen the insert states apexification should precede filling.
  • The insert gives a 6-month in-use period after first opening.

Specification notes

  • Setting time: The insert adds that post placement should follow complete hardening, between 1 week and 1 month.
  • Radiopacity: Stated on the product page, not in the product insert.
Single cone: The insert states it is suitable for single cone or cold lateral condensation.

IFU on file: BioRoot RCS product insert (US), Septodont

BioRoot Flow

Septodont

Composition: Tricalcium silicate, propylene glycol, povidone, calcium carbonate, AEROSIL, zirconium oxide, acrylamide / sodium acryloyldimethyltaurate copolymer, isohexadecane, polysorbate.

Contraindications

  • Hypersensitivity to one or more components
  • Immature or temporary teeth

Handling notes

  • The IFU states the working length should not exceed 2 mm from the radiological apex, to avoid apical extrusion.
  • The IFU states that using it without gutta-percha points jeopardises endodontic and retreatment procedures.
  • May cause eye irritation and skin burn; the IFU requires personal protective equipment.
  • The IFU gives a 4-month in-use period after first opening.

Specification notes

  • Setting time: Measured according to ISO 6876.
  • Radiopacity: The manufacturer's brochure states > 5 mm Al; the IFU value is the labelling value.
  • Solubility: Brochure figure, carrying the manufacturer's own reference.
  • Flow: Brochure figure, carrying the manufacturer's own reference.
  • pH: The IFU states only that the pH is alkaline.
  • Retreatability: The brochure adds 'retreatable in less than 10 min'.
Single cone: The IFU describes completing obturation with a master cone (single cone) or several points (lateral condensation).

IFU on file: BioRoot Flow IFU (US EN), Septodont

EndoSequence BC Sealer / BC Sealer HiFlow

Brasseler USA

Composition: Zirconium oxide, calcium silicates, calcium hydroxide, calcium phosphate monobasic and filler agents.

Contraindications

  • Known allergy to any of the product's ingredients

Handling notes

  • The IFU warns that overfilling may lead to sensitivity, foreign body inflammation, maxillary sinus aspergillosis, paraesthesia from nerve impingement, or surgical removal.
  • The IFU warns against excessive force when applying the material, linking it to pain and syringe plunger breakage.
  • Not tested in pregnant women or nursing mothers.

Specification notes

  • Working time: The FKG-branded IFU for the same chemistry states more than 4 hours; each brand's own IFU is quoted.
  • Setting time: The IFU adds that in very dry root canals setting can take more than 10 hours.
Single cone: The IFU states it is suitable for the single cone and lateral condensation technique.

IFU on file: EndoSequence BC Sealer & BC Sealer HiFlow IFU 4608 REV 11.0

TotalFill BC Sealer / BC Sealer HiFlow

FKG Dentaire

Composition: Calcium silicate compounds, zirconium oxide and calcium hydroxide (SDS). The brochure states up to 50 % calcium silicate and 4 % calcium hydroxide.

Contraindications

  • Known allergy to any of the product's ingredients

Handling notes

  • The IFU warns that overfilling may lead to sensitivity, foreign body inflammation, maxillary sinus aspergillosis, paraesthesia from nerve impingement, or surgical removal.
  • Unset material may cause irritation; the IFU requires personal protective equipment.
  • Not tested on pregnant or nursing mothers.

Specification notes

  • Working time: The Brasseler-branded IFU for the same chemistry states more than 30 minutes; each brand's own IFU is quoted.
  • Setting time: The IFU adds that in very dry root canals setting can take more than 10 hours.
Single cone: The IFU states it is suitable for the single cone and lateral condensation technique.

IFU on file: TotalFill BC Sealer / BC Sealer HiFlow IFU, B-4741A-08.22 REV2

CeraSeal

Meta Biomed

Composition: Calcium silicates, zirconium oxide, thickening agent (IFU). SDS: zirconium dioxide 45–50 %, tricalcium silicate 20–30 %, dicalcium silicate 1–10 %.

Contraindications

  • Primary teeth — the IFU states the product should not be used for milk teeth
  • History of hypersensitivity such as rash or dermatitis
  • Allergy to any component
  • Pregnant or lactating patients

Handling notes

  • The IFU excludes placing it in the canal on its own and calls for a gutta-percha master point.
  • The IFU asks for a rubber dam before use.
  • The IFU asks for moderate syringe pressure and for filling to stay short of the apex.

Specification notes

  • Setting time: ISO 6876:2012. The manufacturer's catalogue and product page state 3.5 h — the IFU value is the labelling value and the conflict is unresolved by the manufacturer.
  • Radiopacity: Catalogue figure. The IFU states only that the material is radiopaque.
  • pH: The catalogue states pH > 12 as well.
Single cone: The IFU states it is suitable for the single cone and lateral condensation technique, but also requires a gutta-percha master point.

IFU on file: CeraSeal IFU (EN), DM-169-3

Bio-C Sealer

Angelus

Composition: Calcium silicate, calcium aluminate, calcium oxide, zirconium oxide, iron oxide, silicon dioxide and dispersing agent.

Contraindications

  • Reported sensitivity to any formula component
  • Expired product or damaged packaging

Handling notes

  • The IFU states the product should be used only after infection control, because the material will not set in an acidic environment.
  • The IFU asks for drying with paper points without over-drying, and states moisture from dentinal tubules initiates setting.
  • Excessive extrusion into the periapical region is to be avoided.
  • Safety and efficacy are not established in vulnerable populations.

Specification notes

  • Radiopacity: Technical-scientific profile, ISO 6876:2012. The IFU states only 'high radiopacity'.
  • Solubility: The same technical profile also reports 0.5–2.5 % in its text — the manufacturer's document is internally inconsistent.
Single cone: The IFU states it can be used with conventional techniques, single cone and thermoplastic obturation, and gives a numbered single-cone sequence.

IFU on file: Bio-C Sealer multilingual IFU, Angelus

Bio-C Sealer ION+

Angelus

Composition: Calcium and magnesium silicate, calcium sulfate, potassium sulfate, calcium oxide, zirconium oxide, silicon dioxide and dispersing agent. The folder states the sealer is resin-free.

Contraindications

  • Known sensitivity to the formula components
  • Expired product or damaged packaging

Handling notes

  • The IFU excludes use without gutta-percha cones.
  • The IFU limits use to canals where infection has been controlled, and states acidic pH from an infected medium may impair setting.
  • Excessive extrusion into the periapical region is to be avoided.
  • Safety and efficacy are not established in pregnancy, lactation, children or adolescents.

Specification notes

  • Radiopacity: Folder figure, ISO 6876:2012. The IFU states only 'high radiopacity'.
  • Film thickness: The folder labels this row 'particle thickness'; it sits between particle size and solubility and reads as film thickness, but the manufacturer does not label it so.
  • pH: The corresponding folder cell was unreadable in the document on file, so no number is quoted from it.
Single cone: The IFU states it can be used with conventional techniques, single cone and thermoplastic obturation, and gives a numbered single-cone sequence.

IFU on file: Bio-C Sealer ION+ IFU (EN/FR/ES/PT), Angelus

Calcium aluminosilicate

BC Universal Sealer

FKG Dentaire

Composition: Calcium aluminosilicate compound, zirconium oxide, filler and thickening agent (IFU). SDS lists zirconium oxide 15–25 %, calcium sulfate dihydrate < 5 %, calcium sodium phosphosilicate < 5 %, propylene glycol 2–7 %, titanium dioxide 2–7 %.

Handling notes

  • The IFU warns against pressing the paste with excess force, linking it to acute pain.
  • The IFU asks that filling stay short of the apex.
  • The IFU keeps the syringe tip no deeper than the coronal third.

Specification notes

  • Setting time: ISO 6876:2012 at 100 % humidity; the IFU adds that in normal root canals setting can take more than 2.5 hours. The brochure separately states initial 5 ± 2 min and final 45 ± 5 min.
  • Radiopacity: Measured according to ISO 6876.
  • Flow: As printed this sits below the ISO 6876 floor of 17 mm for flow; the value is quoted as the manufacturer states it.
  • pH: The same brochure elsewhere states pH > 12.
Single cone: The IFU does not name a single-cone technique; it describes injecting the sealer and then placing gutta-percha points using standard endodontic techniques.

IFU on file: BC Universal Sealer IFU, 20221107 Rev 0

Epoxy resin

AH Plus / AH Plus Jet

Dentsply Sirona

Composition: Paste A: calcium tungstate, Araldite GY 250 and GY 285 epoxy resins, zirconium oxide, silicon dioxide, iron oxide pigments. Paste B: calcium tungstate, zirconium oxide, amantadine, dibenzyldiamine, silicon dioxide, polydimethylsiloxane, tricyclodecane-diamine.

Contraindications

  • History of allergic reaction to epoxy resins or amines

Handling notes

  • The IFU warns that overfilling may cause periapical inflammation or extrusion into the mandibular nerve canal.
  • The SSCP states that eugenol-containing materials may interfere with setting.

Specification notes

  • Working time: The IFU footnotes this as an internal test method.
  • Setting time: ISO 6876:2012. The IFU adds that complete polymerisation needs 7 days at 37 °C.
  • Retreatability: The IFU states fillings can best be removed using thermo-mechanical techniques.
Single cone: The IFU indicates use in combination with root canal points and does not name a single-cone technique.

IFU on file: AH Plus / AH Plus Jet IFU, multilingual, 2023-04-25

AH 26 (silver-free)

Dentsply Sirona

Composition: Resin: bisphenol-A diglycidyl ether 80–100 % (SDS). Powder: methenamine 10–30 % (SDS). The SSCP names bismuth oxide in the filler system.

Handling notes

  • The SDS classifies it as a skin sensitiser (H317).
  • The SSCP notes that discolouration can occur because of bismuth oxide in the filler system.

No manufacturer instructions for use could be obtained for this product.

Salicylate resin with MTA filler

MTA Fillapex

Angelus

Composition: Base paste: salicylate resin, natural resin, calcium tungstate, silicon dioxide, titanium dioxide. Catalyst paste: sulfonamide resin, natural resin, mineral trioxide aggregate, silicon dioxide, titanium dioxide. The IFU states it does not contain eugenol.

Contraindications

  • Allergy to the product's components
  • Expired product or damaged packaging

Handling notes

  • The IFU limits use to canals where the infection has been controlled, and states the material will not function correctly at the acidic pH of an infected environment.
  • The IFU asks that the base and catalyst caps not be interchanged, and states this can harden the product inside the tube.
  • Safety and efficacy are not established in pregnancy, lactation, children or adolescents.

Specification notes

  • Setting time: Stated in the manufacturer's folder and product page, not in the IFU. The product page adds that it sets only in contact with moisture.
  • Film thickness: Measured according to ISO 6876.
  • Solubility: Measured according to ISO 6876.
  • Flow: Measured according to ISO 6876.
Single cone: The IFU carries a numbered single-cone technique section.

IFU on file: MTA-Fillapex multilingual IFU, Angelus, issued 2025-01-17

Silicone (polydimethylsiloxane)

GuttaFlow bioseal

Coltene / Roeko

Composition: Gutta-percha powder, polydimethylsiloxane, platinum catalyst, zirconium dioxide, pigments, bioglass.

Contraindications

  • Deciduous teeth

Handling notes

  • Heat instruments may instantly cure material already placed in the canal; the IFU warns against pulling cured material from the canal walls during warm condensation.
  • The IFU does not recommend using further sealers alongside it, because of possible incompatibility.
  • Irrigant residues may prevent curing.
  • Safety and efficacy are not established for children, pregnant or breastfeeding women.

Specification notes

  • Working time: The IFU states heat reduces working time.
  • Radiopacity: Fact sheet, stated standard ISO 6876.
  • Solubility: The manufacturer's brochure separately reports 0.8 % from internal measurements.
  • Retreatability: Fact-sheet claim carrying the manufacturer's own reference; the IFU is silent on removal.
Single cone: The IFU calls for a master gutta-percha point and excludes applying the material directly into the canal, to avoid overfilling. The fact sheet gives cold obturation as the filling method it recommends.

IFU on file: GuttaFlow bioseal IFU (EN), 30003722 01.24

GuttaFlow 2

Coltene / Roeko

Composition: Gutta-percha powder, polydimethylsiloxane, platinum catalyst, zirconium dioxide, pigments.

Contraindications

  • Deciduous teeth

Handling notes

  • Heat instruments may instantly cure material already placed in the canal.
  • Both components are mixed bubble-free at a ratio of 4:1.
  • Irrigant residues may prevent curing.
  • The IFU gives a three-month in-use period after opening.

Specification notes

  • Working time: The IFU states heat reduces working time.
Single cone: The IFU calls for a master gutta-percha point and excludes applying the material directly into the canal, to avoid overfilling.

IFU on file: GuttaFlow2 IFU (EN), 30005397 01.24

Calcium hydroxide

Sealapex

Kerr

Composition: Catalyst: isobutyl salicylate, bismuth trioxide, titanium dioxide, pigments. Base paste: zinc oxide, polymeric resin, calcium hydroxide (manufacturer catalogue). The product page describes it as a non-eugenol, polymeric calcium hydroxide sealant.

Handling notes

  • No manufacturer IFU was obtained; the catalogue's stated working time is not reproduced here because it is implausible as printed and could not be checked against labelling.

Specification notes

  • Setting time: Catalogue figure; no IFU was obtained for this product.

No manufacturer instructions for use could be obtained for this product.

Pulp Canal Sealer EWT

Kerr

Composition: Not stated in the obtained documents. No manufacturer document could be retrieved for this product.

Handling notes

  • No manufacturer document was obtained. The product is listed here so that its absence from the comparison is explicit rather than silent.

No manufacturer instructions for use could be obtained for this product.

Frequently asked questions

01

Why are some cells blank?

Short answer

Because the manufacturer does not state that value in any document we hold.

  • 01The cell is left blank rather than filled from a study or a competitor's figure, so the gap is visible.
02

Why do two brands of the same chemistry list different working times?

Short answer

EndoSequence BC Sealer and TotalFill BC Sealer share a chemistry and much of their IFU text, yet the Brasseler IFU states more than 30 minutes of working time and the FKG IFU states more than 4 hours.

  • 01Each brand's own instructions for use are quoted rather than reconciled.
03

Does a higher radiopacity or a lower solubility figure mean a better sealer?

Short answer

This page does not rank sealers.

  • 01The figures come from different documents and, where the manufacturer states one, different measurement standards; a brochure number and an IFU number are not comparable in the way a table makes them look.
04

Which sealers name a single-cone technique?

Short answer

The single-cone column records only whether the manufacturer's own instructions for use name that technique.

  • 01Several products that are widely used with a single cone do not name it, and at least one requires a gutta-percha master point explicitly.
Method note

Sixteen products are listed. Where a manufacturer's own documents disagree with each other, the instructions for use are treated as the value and the disagreement is recorded next to it rather than resolved.

Related guides

Endodontic Emergencies→Pain After Root Canal→Cracked Tooth & VRF→Failed Root Canal→Endodontic Surgery→Regenerative Endodontics→Apexification & Apexogenesis→Dental Trauma→Tooth Resorption→Diagnosis & Pulp Classification→Root Canal Treatment Steps→Canal Preparation→Working Length Determination→Irrigation Protocols→Intracanal Medicaments→Obturation Techniques→Vital Pulp Therapy→Complications→Local Anesthesia→Rubber Dam & Isolation→Imaging & CBCT→Restoration After Root Canal→Non-Odontogenic Toothache→Perio-Endo Lesions→Separated Instrument→Root Perforation→Sodium Hypochlorite Accident→Endodontic Flare-Up→Ledge, Transportation & Patency→Sealer Extrusion→Diagnosis Chart→Vertucci Classification→Open NiTi Dataset→What Changed in NiTi IFUs→My Kit→Hands-on Courses (Türkiye)→

Educational content

This database is an educational reference for dental professionals. It records what each manufacturer states about its own sealer in the documentation held on file. Values are not cross-brand ranked or evaluated. A blank cell indicates the property is not stated in the obtained manufacturer documents.

Uzm. Dt. Levent Yüksel

Reviewed by

Uzm. Dt. Levent Yüksel

DDS · Endodontist

Endodontist — DDS, Hacettepe University; endodontics specialty training, Ankara University. 10+ years of clinical experience. Sole author and reviewer of EndoGuide content.

About the authorEditorial policyClinical profile
Obturation guide